Name Henry Horng-Shing Lu
Title Professor
Office Room 418, Assemble Building 1
Fax +886-3-572-8745
Tel
 +886-3-571-2121 ext: 31870
+886-3-5731870
E-mail hslu@stat.nctu.edu.tw
Website Personal Homepage

EDUCATION | EXPERIENCE | FIELDS OF INTEREST | PUBLICATIONS | TECHNICAL REPORTS | COURSES

  • EDUCATION
    • Ph.D. in Statistics, Cornell University, USA, 1994.
    • M.S. in Statistics, Cornell University, USA, 1990.
    • B.S. in Electric Engineering, National Taiwan University, Taiwan, 1986.
  • EXPERIENCE
    • Professor, Institute of Statistics, College of Science, National Chiao Tung University, Taiwan, 2002/2-present.
    • Chairman, Interdisciplinary Sciences Degree Program, College of Science, National Chiao Tung University, Taiwan, 2008/2-present.
    • Director, Institute of Statistics, College of Science, National Chiao Tung University, Taiwan, 2002/8-2005/7.
    • Associate Professor, Institute of Statistics, College of Science, National Chiao Tung University, Taiwan, 1994/8-2002/2.
    • Guest Editor for the Special Issue in Journal of Data Science, July, 2008.
    • Associate Editor for Statistica Sinica, 2005-2008.
    • Associate Editor for Journal of the Chinese Statistical Association, 1995-1997.
    • Teaching and Research Assistant, Cornell University, 1989-1994.
    • Visiting Scholar, Institute of Pure and Applied Mathematics, UCLA, fall, 2000.
    • Visiting Scholar, Department of Biostatistics, Harvard University, winter, spring and summer, 2001.
    • Visiting Scholar, Department of Ecology and Evolution, University of Chicago, USA, summer, 2002-2007, 2006/02-2007/01.
  • FIELDS OF INTEREST

    • statistics, medical images and bioinformatics
  • PUBLICATIONS

    A. Journal Papers:

    1. Lu, H. H.-S., Wells, M. T., and Tiwari, R. C. (1994). Inference for Functions in the Two-Sample Problem with Right Censored Data: With Applications. Journal of the American Statistical Association , 89, 427, 1017-1026.

    2. Chang, Y. L. C., Lander, L. C., Lu, H.-S, and Wells, M. T. (1994). Bayesian Analysis for Fault Location in Distributed Systems. IEEE Transactions on Reliability , 43, 3, 457-465.

    3. Lu, H. H.-S., and Hsieh, F. (1997). Transformation Models for Interval Scale Grouped Data with Applications. Statistica Sinica , 7, 4, 841-854.

    4. Lu, H. H.-S., Chen, C.-M., and Yang, I.-H. (1998). Cross-Reference Weighted Least Square Estimates for Positron Emission Tomography. IEEE Transactions on Medical Imaging , 17, 1, 1-8.

    5. Lu,H. H.-S. (1998). On the Random Number Generator in the Bootstrap. Journal of the Chinese Statistical Association , 36, 2, 127-144.

    6. Chen, C.-M., Lu, H.-S., and Lin, Y.-C. (1998). Evolutionary Snake Model for Ultrasound Image Segmentation: A Preliminary Study. Biomedical Engineering-Applications, Basis and Communications, 10, 2, 110-118.

    7. Tu, K.-Y., Chen, T.-B., Lu, H. H.-S., Liu, R.-S., Chou, K.-L., and Chen, J.-C. (1999). Iterative Image Reconstruction with Random Correction for PET Studies. Annals of Nuclear Medicine and Sciences, 12, 4, 195-200.

    8. Chen, C.-M., Lu, H. H.-S., and Lin, Y.-C. (2000). An Early Vision Based Snake Model for Ultrasound Image Segmentation. Ultrasound in Medicine and Biology, 26, 2, 273-285.

    9. Huang, S.-Y., and Lu, H. H.-S. (2000). Bayesian Wavelet Shrinkage for Nonparametric Mixed-Effects Models. Statistica Sinica, 10, 4, 1021-1040.

    10. Huang, S.-Y., and Lu, H. H.-S. (2001). Extended Gauss-Markov Theorem for Nonparametric Mixed-Effects Models. Journal of Multivariate Analysis, 76, 2, 249-266.

    11. Chen, C.-M., and Lu, H. H.-S. (2001). An Adaptive Snake Model for Ultrasound Image Segmentation: Modified Trimmed Mean Filter, Ramp Integration and Adaptive Weighting Parameters. Ultrasonic Imaging, 22, 214-236.

    12. Chen, C.-M., Lu, H. H.-S., and Han, K.-C. (2001). A Textural Approach Based on Gabor Functions for Texture Edge Detection in Ultrasound Images. Ultrasound in Medicine and Biology, 27, 4, 513-534.

    13. Huang, H.-C., Chen, C.-M., Wang, S.-D., and Lu, H. H.-S. (2001). Adaptive Symmetric Mean Filter: A New Noise Reduction Approach Based on the Slope Facet Model. Applied Optics, 40, 29, 5192-5205.

    14. Tu, K. Y., Chen, T. B., Lu, H. H. S., Liu, R. S., Chen, K. L., Chen, C. M., and Chen, J. C. (2001). Empirical Studies of Cross-Reference Maximum Likelihood Estimate Reconstruction for Positron Emission Tomography. Biomedical Engineering-Applications, Basis and Communications, 13, 1, 1-7.

    15. Chen, C.-M., Lu, H. H. S., and Hsu, Y.-P. (2001). Cross-Reference Maximum Likelihood Estimate Reconstruction for Positron Emission Tomography. Biomedical Engineering-Applications, Basis and Communications, 13, 4, 190-198.

    16. Chen, C.-M., Lu, H. H.-S., and Hsiao, A.-T. (2001). A Dual Snake Model of High Penetrability for Ultrasound Image Boundary Extraction. Ultrasound in Medicine and Biology, 27, 12, 1651-1665.

    17. Gu, Z., Nicolae, D., Lu, H. H.-S., and Li, W.-H. (2002). Rapid divergence in expression between duplicate genes inferred from microarray data. Trends in Genetics, 18, 12, 609-613.

    18. Chen, C.-M., Lu, H. H.-S., and Huang, Y.-S. (2002). Cell-Based Dual Snake Model: A New Approach to Extracting Highly Winding Boundaries in The Ultrasound Images. Ultrasound in Medicine and Biology, 28, 8, 1061-1073.

    19. Chen, C.-M., Lu, H. H.-S., and Su, B.-S. (2002). Cell-Based Region Competition for Ultrasound Image Segmentation. Journal of Medical and Biological Engineering, 22, 2, 59-66.

    20. Lu, H. H.-S., Huang, S.-Y., and Lin, F.-J. (2003). Generalized Cross-Validation for Wavelet Shrinkage in Nonparametric Mixed-Effects Models. Journal of Computational and Graphical Statistics, 12, 3, 714-730.

    21. Chen, C.-M., Lu, H. H.-S., and Chen, Y.-L. (2003). A Discrete Region Competition Approach Incorporating Weak Edge Enhancement for Ultrasound Image Segmentation. Pattern Recognition Letters, 24, 693-704.

    22. Qin, H., Lu, H. H.-S., Wu, W. B., and Li, W.-H. (2003). Evolution of the yeast protein interaction network. PNAS (Proceedings of the National Academy of Sciences of the United States of America), 100, 22, 12820-12824.

    23. Wu, H.-M., and Lu, H. H.-S. (2004). Supervised Motion Segmentation by Spatial-Frequential Analysis and Dynamic Sliced Inverse Regression. Statistica Sinica, 14, 413-430.

    24. Chen, L., Lu, H. H.-S., and Chang, H.-C. (2004). Utilization rates of preventive health services provided for children by the National Health Insurance Program, 1996-2001. Taiwan J Public Health, 23, 1, 37-44.

    25. Zhang, L., Lu, H. H.-S., Chung, W.-Y., Yang, J., and Li, W.-H. (2005). Patterns of Segmental Duplications in the Human Genome. Molecular Biology and Evolution, 22, 1, 135-141.

    26. Li, L., and Lu, H. H.-S. (2005). Explore Biological Pathways from Noisy Array Data by Directed Acyclic Boolean Networks. Journal of Computational Biology, 12, 2, 170-185.

    27. Tsai, H.-K., Lu, H. H.-S., and Li, W.-H. (2005). Statistical methods for identifying yeast cell cycle transcription factors. PNAS (Proceedings of the National Academy of Sciences of the United States of America), 102, 38, 13532-13537.

    28. Ho, J., Hwang, W.-L., Lu, H. H.-S., and Lee, D. T. (2006). Gridding Spot Centers of Smoothly Distorted Microarray Images. IEEE Transactions on Image Processing, 15, 2, 342-354.

    29. Tsai, H.-K., Huang, G. T.-W., Chou, M.-Y., Lu, H. H.-S., and Li, W.-H. (2006). Method for identifying transcription factor binding sites in yeast. Bioinformatics, 22, 14, 1675–1681.

    30. Wu, H.-M., and Lu, H. H.-S. (2007). Iterative Sliced Inverse Regression for Segmentation of Ultrasound and MR Images. Pattern Recognition, 40, 12, 3492-3502.

    31. Chen, T.-B, Chen, J.-C., Lu, H. H.-S., and Liu, R.-S. (2008). MicroPET Reconstruction with Random Coincidence Correction via a Joint Poisson Model. Medical Engineering & Physics, 30, 6, 680-686.

    32. Tzeng, J., Lu, H. H.-S., and Li, W.-H. (2008). Multidimensional Scaling for Large Genomic Data Sets. BMC Bioinformatics, 9:179.

    33. Chen, T.-B., Lu, H. H.-S., Lee, Y.-S., and Lan, H.-J. (2008). Segmentation of cDNA Microarray Images by Kernel Density Estimation. Journal of Biomedical Informatics. (Accepted)

    34. Lu, H. H.-S., Chen, C.-M., Huang, Y.-M.,?and Wu, J.-S. (2008). Computer-Aided Diagnosis of Liver Cirrhosis by Simultaneous Comparisons of the Ultrasound Images of Liver and Spleen. Journal of Data Science, 6, 429-448.

    B. Conference Papers and Records:

    1. Chang, Y. L. C., Lander, L. C., Lu, H.-S., and Wells, M. T. (1993a). Bayesion Analysis for Fault Location in Homogeneous Distributed Systems. Proceedings of the IEEE Symposium on Reliable Distributed Systems, 44-53, Princeton , New Jersey.

    2. Chang, Y. L. C., Lander, L. C., Lu, H.-S., and Wells, M. T. (1993b). Bayesian Inference for Fault Diagnosis in Real-Time Distributed Systems. The Second Asian Test Symposium (ATS”93). 333-338, Beijing.

    3. Lu, H. H.-S., and Chang, Y. L. C. (1995). Issues in the Assignment of Fault Diagnosis Time for Responsive Computing Systems. Proceedings of ISSAT International Conference of Reliability and Quality in Design, 238-242, Orlando , Florida.

    4. Lu, H. H.-S., and Tseng, W.-J. (1997). On Accelerated Cross-Reference Maximum Likelihood Estimates for Positron Emission Tomography. Proceedings of the IEEE Nuclear Science Symposium, Volume 2, 1484-1488.

    5. Chen, J. C., Tu, K. Y., Lu, H. H.-S., Chen, T. B., Chou, K. L., and Liu, R. S. (1998). Statistical Image Reconstruction for PET Studies. The Biomedical Engineering Society 1998 Annual Symposium, 71-72.

    6. Tu, K. Y., Chen, J. C., Lu, H. H.-S., Chen, T. B., Chou, K. L., and Liu, R. S. (1999). Iterative Image Reconstruction with Random Coincidence Correction for PET Studies. The Biomedical Engineering Society 1999 Annual Symposium, 357-358.

    7. Chen, J. C., Liu, R. S., Tu, K. Y., Lu, H. H. S., Chen, T. B., and Chou, K. L. (2000). Iterative Image Reconstruction with Random Correction for PET studies. Proceedings of the Society of Photo-Optical Instrumentation Engineers, 3979, 1218-1229.

    8. Chen, J. C., Tu, K. Y., Lu, H. H.-S., Chen, T. B., Chou, K. L., and Liu, R. S. (2000). Iterative Image Reconstruction with Random Correction for PET Studies. SPIE medical imaging 2000 symposium.

    9. Tu, K. Y., Chen, J. C., Lu, H. H.-S., Chen, T. B., Chou, K. L., and Liu, R. S. (2000). Random Correction Using Iterative Reconstruction for PET. European Association of Nuclear Medicine Annual Congress.

    10. Lu, H. H.-S., Chen, C.-M., and Wu, J.-S. (2001). Statistical Analysis of Liver Cirrhosis in Ultrasound Images by Fractal Dimension, Dimension Reduction and Classification Trees. The 5th World Multi-Conference on Systemics, Cybernetics and Informatics (SCI 2001) , Vol. XIII, Part II, 351-356.

    11. Chen, C.-M., and Lu, H. H.-S., (2001). Sonographic Tumor Boundary Detection for Image-Guided Brain Surgery. The 5th World Multi-Conference on Systemics, Cybernetics and Informatics (SCI 2001), Vol. XIII, Part II, 339-344.

    12. Lu, H. H.-S., and Wu, H.-M. (2003). On Visualization, Screening, and Classification of Cell Cycle-Regulated Genes in Yeast. The 14th International Conference on Genome Informatics (GIW2003), 344-345.

    13. Chen, C.-H., Lu, H. H.-S., Liao, C.-T., Chen, C.-h., Yang, U.-C., Lee, Y.-S. (2003). Gene Expression Analysis Refining System (GEARS) via Statistical Approach: A Preliminary Report. The 14th International Conference on Genome Informatics (GIW2003), 316-317.

    14. Ho, J., Hwang, W.-L., Lu, H. H.-S., and Lee, D. T. (2005). Gridding the spot centers of Microarray Images. European Signal Processing Conference, Antalya, Turkey, September 4-8.

    15. Lu, H. H.-S. (2006). Reconstruction, Visualization and Analysis of Medical Images. Compstat 2006 Satellite Workshop on Data and Information Visualization, Berlin, Germany, August 23-25.

    16. Chen, P. Y., Chen, T.-B., Chen, C.-J., Li, G.-C.,Lu, H. H.-S. (2007). Information Visualization and Fusion for Barcodes of Life in Environment and Society. The Second International Barcode of Life Conference, Taipei, Taiwan, September 17-21.

    17. Liu, P.-L., Lu, H. H.-S., Chiang. A.-S. (2007). Automatic Classification of 3D Drosophila Calyx Images. 2007 National Computation Symposium, Taichung, Taiwan, December 20-21.

    C. Book Chapters:

    1. Lu, H. H.-S. (2008).Reconstruction, Visualization, and Analysis of Medical Images. Handbook of Computational Statistics (Volume III) Data Visualization, C. -h. Chen, W. Hardle, and A. Unwin (eds), Springer-Verlag, 813-830.

     

  • Technical Reports

README

GCV-long.pdf

blupwave.pdf

gm.pdf

DSIR-revised.pdf

 

  • Courses

Course Homepage of Statistical Computing (Spring 2008)
Course Homepage of Topics of Statistics in Bioinformatics (Fall 2007)
Course Homepage of Statistics (Fall 2007)
Course Homepage of Statistical Consulting (Spring 2005)
Course Homepage of Statistical Methods in Image Analysis (Spring 1997)
Statistical Applications in Medical Images and Bioinformatics
盧鴻興 (2002), 還原統計的真正面貌－評<統計，改變了世界>, “[科學月刊], 第 33卷 第 12期, pp.1094-1095