hslu

Name

Henry Horng-Shing Lu

Title

Professor

Office

Institute of Statistics, National Chiao Tung University, Assembly Building I, 1001 Ta Hsueh Road, Hsinchu 30010, Taiwan

Fax

+886-3-572-8745

Tel

+886-3-571-2121 ext: 31870
+886-3-5731870

E-mail

hslu@stat.nctu.edu.tw

Website

http://www.stat.nctu.edu.tw/~misg/




EDUCATION

  • Ph.D. in Statistics, Cornell University, USA, 1994.
  • M.S. in Statistics, Cornell University, USA, 1990.
  • B.S. in Electric Engineering, National Taiwan University, Taiwan, 1986.

EXPERIENCE

  • Dean, College of Science, National Chiao Tung University, Taiwan, 2011/8- present.
  • Professor, Institute of Statistics, College of Science, National Chiao Tung University, Taiwan, 2002/2-present.
  • Chairman, Interdisciplinary Sciences Degree Program, College of Science, National Chiao Tung University, Taiwan, 2008/2-2011/7.
  • Director, Institute of Statistics, College of Science, National Chiao Tung University, Taiwan, 2002/8-2005/7.
  • Associate Professor, Institute of Statistics, College of Science, National Chiao Tung University, Taiwan, 1994/8-2002/1.
  • Co-editor for Handbook of Statistical Bioinformatics, Springer, 2011. Reference Link
  • Guest Editor for the Special Issue in International Journal of Systems and Synthetic Biology, 2010.
  • Guest Editor for the Special Issue in Journal of Data Science, July, 2008.
  • Associate Editor for Statistica Sinica, 2005-2008.
  • Associate Editor for Journal of the Chinese Statistical Association, 1995-1997, 2008-2010.
  • Teaching and Research Assistant, Cornell University, 1989-1994.
  • Visiting Scholar, Institute of Pure and Applied Mathematics, UCLA, fall, 2000.
  • Visiting Scholar, Department of Biostatistics, Harvard University, winter, spring and summer, 2001.
  • Visiting Scholar, Department of Ecology and Evolution, University of Chicago, USA, summer, 2002-2007, 2006/02-2007/01.

HONOR

  • Elected member, International Statistical Institute (ISI), 2011. Link
  • Board of Directors, International Chinese Statistical Association (ICSA) Board, 2012-2014. Reference Link

FIELDS OF INTEREST

  • Statistics and Applications

PUBLICATIONS

    • Journal Articles
      1. Lu, H. H.-S., Wells, M. T., and Tiwari, R. C., "Inference for Functions in the Two-Sample Problem with Right Censored Data: With Applications" , Journal of the American Statistical Association , 89, 427, 1017-1026. 1994. (SCI) Reference Link
      2. Chang, Y. L. C., Lander, L. C., Lu, H.-S, and Wells, M. T., "Bayesian Analysis for Fault Location in Distributed Systems" , IEEE Transactions on Reliability , 43, 3, 457-465. 1994. (SCI) Reference Link
      3. Lu, H. H.-S., and Hsieh, F., "Transformation Models for Interval Scale Grouped Data with Applications" , Statistica Sinica , 7, 4, 841-854. 1997. (SCI) Reference Link
      4. Lu, H. H.-S., Chen, C.-M., and Yang, I.-H., "Cross-Reference Weighted Least Square Estimates for Positron Emission Tomography" , IEEE Transactions on Medical Imaging , 17, 1, 1-8. 1998. (SCI) Reference Link
      5. Lu, H. H.-S., "On the Random Number Generator in the Bootstrap" , Journal of the Chinese Statistical Association , 36, 2, 127-144, 1998 Reference Link
      6. Chen, C.-M., Lu, H.-S., and Lin, Y.-C., "Evolutionary Snake Model for Ultrasound Image Segmentation: A Preliminary Study" , Biomedical Engineering-Applications, Basis and Communications, 10, 2, 110-118. 1998. (EI) Reference Link
      7. Tu, K.-Y., Chen, T.-B., Lu, H. H.-S., Liu, R.-S., Chou, K.-L., and Chen, J.-C., "Iterative Image Reconstruction with Random Correction for PET Studies" , Annals of Nuclear Medicine and Sciences, 12, 4, 195-200. 1999. Reference Link
      8. Chen, C.-M., Lu, H. H.-S., and Lin, Y.-C., "An Early Vision Based Snake Model for Ultrasound Image Segmentation" , Ultrasound in Medicine and Biology, 26, 2, 273-285. 2000. (SCI) Reference Link
      9. Huang, S.-Y., and Lu, H. H.-S., "Bayesian Wavelet Shrinkage for Nonparametric Mixed-Effects Models" , Statistica Sinica, 10, 4, 1021-1040. 2000. (SCI) Reference Link
      10. Chen, C.-M., and Lu, H. H.-S., "An Adaptive Snake Model for Ultrasound Image Segmentation: Modified Trimmed Mean Filter, Ramp Integration and Adaptive Weighting Parameters" , Ultrasonic Imaging, 22, 214-236. 2000. (SCI) Reference Link
      11. Huang, S.-Y., and Lu, H. H.-S., "Extended Gauss-Markov Theorem for Nonparametric Mixed-Effects Models" , Journal of Multivariate Analysis, 76, 2, 249-266. 2001. (SCI) Reference Link
      12. Chen, C.-M., Lu, H. H.-S., and Han, K.-C., "A Textural Approach Based on Gabor Functions for Texture Edge Detection in Ultrasound Images" , Ultrasound in Medicine and Biology, 27, 4, 513-534. 2001. (SCI) Reference Link
      13. Huang, H.-C., Chen, C.-M., Wang, S.-D., and Lu, H. H.-S., "Adaptive Symmetric Mean Filter: A New Noise Reduction Approach Based on the Slope Facet Model" , Applied Optics, 40, 29, 5192-5205. 2001. (SCI) Reference Link
      14. Tu, K. Y., Chen, T. B., Lu, H. H. S., Liu, R. S., Chen, K. L., Chen, C. M., and Chen, J. C., "Empirical Studies of Cross-Reference Maximum Likelihood Estimate Reconstruction for Positron Emission Tomography" , Biomedical Engineering-Applications, Basis and Communications, 13, 1, 1-7. 2001. (EI) Reference Link
      15. Chen, C.-M., Lu, H. H. S., and Hsu, Y.-P., "Cross-Reference Maximum Likelihood Estimate Reconstruction for Positron Emission Tomography" , Biomedical Engineering-Applications, Basis and Communications, 13, 4, 190-198. 2001. (EI) Reference Link
      16. Chen, C.-M., Lu, H. H.-S., and Hsiao, A.-T., "A Dual Snake Model of High Penetrability for Ultrasound Image Boundary Extraction" , Ultrasound in Medicine and Biology, 27, 12, 1651-1665. 2001. (SCI) Reference Link
      17. Gu, Z., Nicolae, D., Lu, H. H.-S., and Li, W.-H., "Rapid divergence in expression between duplicate genes inferred from microarray data" , Trends in Genetics, 18, 12, 609-613. 2002. (SCI) Reference Link
      18. Chen, C.-M., Lu, H. H.-S., and Huang, Y.-S., "Cell-Based Dual Snake Model: A New Approach to Extracting Highly Winding Boundaries in The Ultrasound Images" , Ultrasound in Medicine and Biology, 28, 8, 1061-1073. 2002. (SCI) Reference Link
      19. Chen, C.-M., Lu, H. H.-S., and Su, B.-S., "Cell-Based Region Competition for Ultrasound Image Segmentation" , Journal of Medical and Biological Engineering, 22, 2, 59-66, 2002. Reference Link
      20. Chen, C.-M., Lu, H. H.-S., and Chen, Y.-L., "A Discrete Region Competition Approach Incorporating Weak Edge Enhancement for Ultrasound Image Segmentation" , Pattern Recognition Letters, 24, 693-704. 2003. (SCI) Reference Link
      21. Lu, H. H.-S., Huang, S.-Y., and Lin, F.-J., "Generalized Cross-Validation for Wavelet Shrinkage in Nonparametric Mixed-Effects Models" , Journal of Computational and Graphical Statistics, 12, 3, 714-730. 2003. (SCI) Reference Link
      22. Qin, H., Lu, H. H.-S., Wu, W. B., and Li, W.-H., "Evolution of the yeast protein interaction network" , PNAS (Proceedings of the National Academy of Sciences of the United States of America), 100, 22, 12820-12824. 2003. (SCI) Reference Link
      23. Wu, H.-M., and Lu, H. H.-S., "Supervised Motion Segmentation by Spatial-Frequential Analysis and Dynamic Sliced Inverse Regression" , Statistica Sinica, 14, 413-430. 2004. (SCI) Reference Link
      24. Chen, L., Lu, H. H.-S., and Chang, H.-C., "Utilization rates of preventive health services provided for children by the National Health Insurance Program, 1996-2001" , Taiwan Journal of Public Health, 23, 1, 37-44, 2004. Reference Link
      25. Zhang, L., Lu, H. H.-S., Chung, W.-Y., Yang, J., and Li, W.-H., "Patterns of Segmental Duplications in the Human Genome" , Molecular Biology and Evolution, 22, 1, 135-141. 2005. (SCI) Reference Link
      26. Li, L., and Lu, H. H.-S., "Explore Biological Pathways from Noisy Array Data by Directed Acyclic Boolean Networks" , Journal of Computational Biology, 12, 2, 170-185. 2005. (SCI) Reference Link
      27. Tsai, H.-K., Lu, H. H.-S., and Li, W.-H., "Statistical methods for identifying yeast cell cycle transcription factors" , PNAS (Proceedings of the National Academy of Sciences of the United States of America), 102, 38, 13532-13537. 2005. (SCI) Reference Link
      28. Ho, J., Hwang, W.-L., Lu, H. H.-S., and Lee, D. T., "Gridding Spot Centers of Smoothly Distorted Microarray Images" , IEEE Transactions on Image Processing , 15, 2, 342-354. 2006. (SCI) Reference Link
      29. Tsai, H.-K., Huang, G. T.-W., Chou, M.-Y., Lu, H. H.-S., and Li, W.-H., "Method for identifying transcription factor binding sites in yeast" , Bioinformatics, 22, 14, 1675–1681. 2006. (SCI) Reference Link
      30. Wu, H.-M., and Lu, H. H.-S., "Iterative Sliced Inverse Regression for Segmentation of Ultrasound and MR Images" , Pattern Recognition, 40, 12, 3492-3502 2007. (SCI) Reference Link
      31. Chen, T.-B, Chen, J.-C., Lu, H. H.-S., and Liu, R.-S., "MicroPET Reconstruction with Random Coincidence Correction via a Joint Poisson Model" , Medical Engineering & Physics, 30, 6, 680-686. 2008. (SCI) Reference Link
      32. Tzeng, J., Lu, H. H.-S., and Li, W.-H., "Multidimensional Scaling for Large Genomic Data Sets" , BMC Bioinformatics, 9:179. 2008. (SCI) Reference Link
      33. Chen, T.-B., Lu, H. H.-S., Lee, Y.-S., and Lan, H.-J., "Segmentation of cDNA Microarray Images by Kernel Density Estimation" , Journal of Biomedical Informatics, 41, 1021–1027. 2008. (SCI) Reference Link
      34. Lu, H. H.-S., Chen, C.-M., Huang, Y.-M., and Wu, J.-S., "Computer-Aided Diagnosis of Liver Cirrhosis by Simultaneous Comparisons of the Ultrasound Images of Liver and Spleen" , Journal of Data Science, 6, 429-448, 2008. Reference Link
      35. Scharfe, C., Lu, H. H.-S., Neuenburg, J. K., Allen, E. A., Li, G.-C., Klopstock, T., Cowan, T. M., Enns, G. M., and Davis, R. W., "Mapping Gene Associations in Human Mitochondria using Clinical Disease Phenotypes" , PLoS Computational Biology 5(4): e1000374. 2009. (SCI) Reference Link
      36. Tu, K. K.-W., Lee, J. C.-s., and Lu, H. H.-S., "A Novel Statistical Method for Automatically Partitioning Tools According to Engineers' Tolerance Control in Process Improvement" , IEEE Transactions on Semiconductor Manufacturing. 22, 3, 373 - 380. 2009. (SCI) Reference Link
      37. Emerson, J. J., Hsieh, L.-C., Sung, H.-M., Wang, T.-Y., Huang, C.-J., Lu, H. H.-S., Lu, M.-Y. J., Wu, S.-H., and Li, W. H., "Natural selection on cis and trans regulation in yeasts" , Genome Research, 20, 826-836. 2010. (SCI) Reference Link
      38. Deng, L.-Y. , Lu, H. H.-S., and Chen, T.-B., "64-Bit and 128-bit DX random number generators" , Computing,  89, 1, 27-43. 2010. (SCI) Reference Link
      39. Cheng, J. H., Wang, Y., Chen, P. Y., Chen, T.-B., Chen, C.-J., Li, G.-C., and Lu, H. H.-S., "Mine Barcode of Life: Information Visualization and Fusion for the Environment and Society" , International Journal of Systems and Synthetic Biology, 1(1), 63-70. 2010.  Reference Link
      40. Lu, H. H.-S., and Wu, H. M.,"Visualization, Screening, and Classification of Cell Cycle-Regulated Genes in Yeast" , International Journal of Systems and Synthetic Biology, 1(2), 185-198, 2010.
      41. Wang, H., Lu, H. H.-S., Chueh, T.-H.,"Constructing Biological Pathways by a Two-Step Counting Approach" , PLoS ONE 6(6): e20074, 2011. (SCI) Reference Link
      42. Deng, L.-Y. , Shiau, J.-J. H., and Lu, H. H.-S.,"Large-order multiple recursive generators with modulus $2^{31}-1$" , INFORMS Journal on Computing, Published online before print, October 17, 2011. Published in Vol. 24, No. 4, Fall 2012, pp. 636–647. (SCI) Reference Link
      43. Deng, L.-Y. , Shiau, J.-J. H., and Lu, H. H.-S., "Efficient computer search of large-order multiple recursive pseudo-random number generators" , Journal of Computational and Applied Mathematics, 236, 3228– 3237, 2012. (SCI) Reference Link
      44. Chiang, S, Swamy, K. B., Hsu, T. W., Tsai, Z. T., Lu, H. H.-S., Wang, D., Tsai, H. K., "Analysis of the association between transcription factor binding site variants and distinct accompanying regulatory motifs in yeast" , Gene. 2012 Jan 10;491(2):237-45. Epub 2011 Sep 16. (SCI) Reference Link
      45. Chueh, T.-H., and Lu, H. H.-S., "Inference of Biological Pathway from Gene Expression Profiles by Time Delay Boolean Networks" , PLoS ONE 7(8): e42095, 2012. (SCI) Reference Link
      46. Suen, S., Lu, H. H.-S., and Yeang, C. H., "Evolution of domain architectures and catalytic functions of enzymes in metabolic systems" , Genome Biology and Evolution, 2012. (SCI) [Epub ahead of print] Reference Link
      47. Chen, T.-B, Chen, J.-C., and Lu, H. H.-S., "Segmentation of 3D microPET Images of the Rat Brain via the Hybrid Gaussian Mixture Method with Kernel Density Estimation" , Journal of X-ray Science and Technology, 2012, 20, 339-349. (SCI) Reference Link
      48. Chueh, T. H., Chen, T.-B., Lu, H. H.-S., Ju, S.-S., Tao, T.-H., and Shaw, J. H., "Statistical Prediction of Emotional States by Physiological Signals with MANOVA and Machine Learning" , International Journal of Pattern Recognition and Artificial Intelligence, 2012, 26, 1250008. (SCI) Reference Link
    • Conference Papers
    1. Chang, Y. L. C., Lander, L. C., Lu, H.-S., and Wells, M. T., "Bayesion Analysis for Fault Location in Homogeneous Distributed Systems" , Proceedings of the IEEE Symposium onReliable Distributed Systems, 44-53, Princeton , New Jersey. 1993. (EI)
    2. Chang, Y. L. C., Lander, L. C., Lu, H.-S., and Wells, M. T., "Bayesian Inference for Fault Diagnosis in Real-Time Distributed Systems" , The Second Asian Test Symposium (ATS」93). 333-338, Beijing., 1993.
    3. Lu, H. H.-S., and Chang, Y. L. C., "Issues in the Assignment of Fault Diagnosis Time for Responsive Computing Systems" , Proceedings of ISSAT International Conference of Reliability and Quality in Design, 238-242, Orlando , Florida., 1995.
    4. Lu, H. H.-S., and Tseng, W.-J., "On Accelerated Cross-Reference Maximum Likelihood Estimates for Positron Emission Tomography" , Proceedings of the IEEE Nuclear Science Symposium, Volume 2, 1484 -1488. 1997. (EI)
    5. Chen, J. C., Tu, K. Y., Lu, H. H.-S., Chen, T. B., Chou, K. L., and Liu, R. S., "Statistical Image Reconstruction for PET Studies" , The Biomedical Engineering Society 1998 Annual Symposium, 71-72., 1998.
    6. Tu, K. Y., Chen, J. C., Lu, H. H.-S., Chen, T. B., Chou, K. L., and Liu, R. S., "Iterative Image Reconstruction with Random Coincidence Correction for PET Studies" , The Biomedical Engineering Society 1999 Annual Symposium, 357-358., 1999.
    7. Chen, J. C., Liu, R. S., Tu, K. Y., Lu, H. H. S., Chen, T. B., and Chou, K. L., "Iterative Image Reconstruction with Random Correction for PET studies" , Proceedings of the Society of Photo-Optical Instrumentation Engineers, 3979, 1218-1229. 2000. (EI) Reference Link
    8. Chen, J. C., Tu, K. Y., Lu, H. H.-S., Chen, T. B., Chou, K. L., and Liu, R. S., "Iterative Image Reconstruction with Random Correction for PET Studies" , SPIE medical imaging 2000 symposium., 2000.
    9. Tu, K. Y., Chen, J. C., Lu, H. H.-S., Chen, T. B., Chou, K. L., and Liu, R. S., "Random Correction Using Iterative Reconstruction for PET" , European Association of Nuclear Medicine Annual Congress., 2000.
    10. Lu, H. H.-S., Chen, C.-M., and Wu, J.-S., "Statistical Analysis of Liver Cirrhosis in Ultrasound Images by Fractal Dimension, Dimension Reduction and Classification Trees" , The 5th World Multi-Conference on Systemics, Cybernetics and Informatics (SCI 2001), Vol. XIII, Part II, 351-356., 2001.
    11. Chen, C.-M., and Lu, H. H.-S., "Sonographic Tumor Boundary Detection for Image-Guided Brain Surgery" , The 5th World Multi-Conference on Systemics, Cybernetics and Informatics (SCI 2001), Vol. XIII, Part II, 339-344., 2001.
    12. Lu, H. H.-S., and Wu, H.-M., "On Visualization, Screening, and Classification of Cell Cycle-Regulated Genes in Yeast" , The 14th International Conference on Genome Informatics (GIW2003), 344-345., 2003.
    13. Chen, C.-H., Lu, H. H.-S., Liao, C.-T., Chen, C.-h., Yang, U.-C., Lee, Y.-S., "Gene Expression Analysis Refining System (GEARS) via Statistical Approach: A Preliminary Report" , The 14th International Conference on Genome Informatics (GIW2003), 316-317., 2003.
    14. Ho, J., Hwang, W.-L., Lu, H. H.-S., and Lee, D. T., "Gridding the spot centers of Microarray Images" , European Signal Processing Conference, Antalya, Turkey, September 4-8., 2005.
    15. Lu, H. H.-S, "Reconstruction, Visualization and Analysis of Medical Images" , Compstat 2006 Satellite Workshop on Data and Information Visualization, Berlin, Germany, August 23-25., 2006.
    16. Chen, P. Y., Chen, T.-B., Chen, C.-J., Li, G.-C.,Lu, H. H.-S., "Information Visualization and Fusion for Barcodes of Life in Environment and Society" , The Second International Barcode of Life Conference, Taipei, Taiwan, September 17-21., 2007.
    17. Liu, P.-L., Lu, H. H.-S., Chiang. A.-S., "Automatic Classification of 3D Drosophila Calyx Images" , 2007 National Computation Symposium, Taichung, Taiwan, December 20-21., 2007.
    18. Wu, T.-Y., Juan, H. H., Lu, H. H.-S., Chiang. A.-S., "A Crosstalk Tolerated Neural Segmentation Methodology for Brainbow Images" , International Symposium on Applied Sciences In Biomedical and Communication Technologies (ACM ISABEL), 2011.
    19. Wu, T.-Y., Juan, H. H., Lu, H. H.-S., "Improved Spectral Matting By Iterative K-Means Clustering And The Modularity Measure" , IEEE International Conference on Acoustics, Speech, and Signal Processing (IEEE ICASSP), 2012.

  • Books and Book Chapters:

    1. Lu, H. H.-S. 2008: Reconstruction, Visualization, and Analysis of Medical Images. Handbook of Computational Statistics (Volume III) Data Visualization, C. -h. Chen, W. Hardle, and A. Unwin (eds), Springer-Verlag, 813-830. Reference Link
    2. Chueh, T.-H., Lu, H. H.-S. 2011: Boolean Networks. Handbook of Statistical Bioinformatics, H. H.-S. Lu, B. Scholkopf, and H. Zhao (eds), Springer-Verlag.Reference Link
    3. Lu, H. H.-S., Schölkopf, B., Zhao, H. (eds) 2011: Handbook of Statistical Bioinformatics. Springer-Verlag. Reference Link
  • Technical Reports
    1. Su-Yun Huang and Henry Horng-Shing Lu, "BAYESIAN WAVELET SHRINKAGE FOR NONPARAMETRIC MIXED-EFFECTS MODELS" , Attach FileAttach File Adobe PDF
    2. Su-Yun Huang & Henry Horng-Shing Lu, "Extended Gauss-Markov Theorem for Nonparametric Mixed-Effects Models" , Attach FileAttach File Adobe PDF
    3. Han-Ming Wu and Henry Horng-Shing Lu, "Supervised Motion Segmentation by Spatial-Frequential Analysis and Dynamic Sliced Inverse Regression" , Attach FileAttach File Adobe PDF
    4. Henry Horng-Shing Lu, Su-Yun Huang, Fang-Jiun Lin, "Generalized Cross-Validation for Wavelet Shrinkage in Nonparametric Mixed-Effects Models" , 2002-08 Attach FileAttach File Adobe PDF
  • Others
    1. Lu, H. H.-S., "Statistical Applications in Medical Images and Bioinformatics" , Reference LinkReference Link
    2. Lu, H. H.-S., "Book review for "The Lady Tasting Tea: How Statistics Revolutionized Science in the Twentieth Century"" , Science Monthly, 33, 12, pp. 1094-1095, 2002 Reference LinkReference Link
    3. Lu, H. H.-S., "Course Homepage of Statistical Consulting (Spring 2005)" , 2005. Reference LinkReference Link
    4. Lu, H. H.-S., "Course Homepage of Topics of Statistics in Bioinformatics (Fall 2007)" , 2007 Reference LinkReference Link
    5. Lu, H. H.-S., "Course Homepage of Statistical Computing (Spring 2012)" , 2012 Reference LinkReference Link
    6. Lu, H. H.-S., "Course Homepage of Statistical Learning (Fall 2012)" , 2012 Reference LinkReference Link
    7. Lu, H. H.-S., "Course Homepage of Statistics (Fall 2010)" , 2010 Reference LinkReference Link
    8. Lu, H. H.-S., "Course Homepage of Multivariate Analysis (Spring 2013)" , 2013 Reference LinkReference Link

 

 

The Chinese Version: http://www.stat.nctu.edu.tw/~misg/